Dyslipidemia has long been recognised as a risk factor for atherosclerosis in T2DM patients. Diabetes is frequently associated with various patterns of dyslipidemia, which may increase atherogenic risk. Although patients with diabetes do not have significant increases in plasma LDL cholesterol levels, these levels are still predictive of cardiovascular risk. Diabetes causes LDL particles to be smaller and denser than normal LDL. These small, dense triglyceride-rich LDL particles are particularly dangerous. Small dense LDL particles are more prone to oxidation, especially in the presence of poor glucose control.

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